Pharmaceutical Strategy to Protect Skin Barrier Function
نویسندگان
چکیده
منابع مشابه
The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier?
Infant skin is different from adult in structure, function, and composition. Despite these differences, the skin barrier is competent at birth in healthy, full-term neonates. The primary focus of this paper is on the developing skin barrier in healthy, full-term neonates and infants. Additionally, a brief discussion of the properties of the skin barrier in premature neonates and infants with ab...
متن کاملSkin barrier function and stratum corneum hydration
Under normal circumstances, epidermis must be as impermeable as possible except for a small amount of water loss to hydrate the outer layers of the SC. Although all living cells require water to function, some “dead” cells also require water to be metabolically active. As it is the case of corneocytes, epidermis must retain sufficient water to (a) hydrate the outer layers of the SC to maintain ...
متن کاملPermeability barrier function of skin exposed to ionizing radiation.
OBJECTIVE To characterize the epidermal permeability barrier function of skin during exposure to ionizing radiation. DESIGN A prospective cohort study. SETTING University hospital medical center. PATIENTS Fifteen women receiving local radiation therapy (5000-6000 rad [50-60 Gy]) following breast-conserving surgery for breast cancer. MAIN OUTCOME MEASURES Clinical symptoms and transepide...
متن کاملLipids and barrier function of the skin.
The purpose of the present manuscript is to review the chemical and physical properties of epidermal lipids and to relate these properties to the formation and function of the permeability barrier of the skin. Lipids accumulate in small organelles known as lamellar granules as epidermal keratinocytes differentiate. This lipid is extruded into the intercellular spaces where it undergoes enzymati...
متن کاملCeramides and barrier function in healthy skin.
Lipids in the stratum corneum are key components in the barrier function of the skin. Changes in lipid composition related to eczematous diseases are well known, but limited data are available on variations within healthy skin. The objective of the present study was to compare ceramide subgroups and ceramide/cholesterol ratios in young, old, male and female healthy skin. A total of 55 participa...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2019
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.19-00181-f